Irit Akirav Selected Research

cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)

1/2020	Neuropeptide Y and cannabinoids interaction in the amygdala after exposure to shock and reminders model of PTSD.
1/2018	Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD.
1/2018	Role of endocannabinoids in the hippocampus and amygdala in emotional memory and plasticity.
1/2018	Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD.
10/2017	Cannabinoids prevent the differential long-term effects of exposure to severe stress on hippocampal- and amygdala-dependent memory and plasticity.
1/2017	The effects of enhancing endocannabinoid signaling and blocking corticotrophin releasing factor receptor in the amygdala and hippocampus on the consolidation of a stressful event.
1/2016	Sex differences in hippocampal response to endocannabinoids after exposure to severe stress.

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Irit Akirav Research Topics

Disease

13	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2020 - 10/2010
11	Shock 01/2020 - 11/2014
4	Mental Disorders (Mental Disorder) 01/2021 - 01/2016
3	Wounds and Injuries (Trauma) 01/2018 - 01/2012
2	Cognitive Dysfunction 01/2021 - 01/2012
2	Anhedonia 01/2018 - 01/2018
2	Anxiety Disorders (Anxiety Disorder) 05/2016 - 04/2013
1	Schizophrenia (Dementia Praecox) 01/2022
1	Long Term Adverse Effects 01/2016
1	Weight Gain 03/2014
1	Pain (Aches) 10/2010

Drug/Important Bio-Agent (IBA)

17	CannabinoidsIBA 01/2021 - 01/2012
9	EndocannabinoidsIBA 01/2020 - 10/2010
7	cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)IBA 01/2020 - 01/2016
6	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 01/2020 - 01/2016
3	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2018 - 10/2017
2	anandamide (arachidonylethanolamide)IBA 01/2020 - 01/2018
2	GlucocorticoidsIBA 10/2017 - 09/2013
2	Cannabinoid Receptors (Cannabinoid Receptor)IBA 09/2013 - 01/2012
2	Pharmaceutical PreparationsIBA 04/2013 - 10/2010
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022
1	Glutamic Acid (Glutamate)FDA Link 01/2022
1	gamma-Aminobutyric Acid (GABA)IBA 01/2022
1	Dronabinol (THC)FDA LinkGeneric 01/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2020
1	Neuropeptide YIBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	HydrolasesIBA 01/2018
1	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018
1	Mifepristone (RU 486)FDA Link 10/2017
1	CateninsIBA 01/2017
1	beta CateninIBA 01/2017
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2017
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2016
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 11/2014
1	Sucrose (Saccharose)IBA 03/2014
1	CB2 Cannabinoid ReceptorIBA 09/2013
1	N-(4-hydroxyphenyl)arachidonylamide (AM404)IBA 10/2010
1	AM 251 (AM251)IBA 10/2010

Therapy/Procedure

3	Therapeutics 01/2020 - 05/2016